That would be nice indeed, but I dont (with my limited build experience) think this is possible and at the same time get something good out of it. In order to get the juicy stuff you need as many lvl as SD as possible (25-30)(shadowstep etc etc) which I figure would be the reason why choosing SD in the first place. Also, going mortal strike with a assasin is calculated out of Assasins lvl IIRC, which makes a splash atleast with the good from both sides impossible. You also need some kind of fighter lvl to up the AB and dmg, which historically has been low on SD.
Combining all those things seems imposible to me, but again some super genious will probably find a solution to this too in the near future, maybe we will get flooded with porting assasins bouncing all over, cursing, and then instakill everything insight even before the clerics get off their first plode, or mages get their disintergrate warmed up ? (Right after that they will certainly be hit with the nerf bat)